ruizgenin
CAS No.:
41743-71-9
M. Wt:
432.63600
M. Fa:
C27H44O4
InChI Key:
-
Names and Identifiers of ruizgenin
CAS Number |
41743-71-9 |
|---|---|
IUPAC Name |
(1R,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S,18S,19R)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-16,19-diol |
Canonical SMILES |
C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4C[C@H]([C@@H]6[C@@]5(CC[C@@H](C6)O)C)O)C)C)OC1 |
Physical and chemical properties of ruizgenin
Boiling Point |
550.5ºC at 760 mmHg |
|---|---|
Density |
1.16g/cm3 |
Exact Mass |
432.32400 |
Flash Point |
286.7ºC |
Index of Refraction |
1.564 |
LogP |
4.76460 |
Molecular Formula |
C27H44O4 |
Molecular Weight |
432.63600 |
PSA |
58.92000 |
Applications of ruizgenin
Beta-Chlorogenin has several applications in various fields:
- Pharmaceuticals: Its antiviral and anticancer properties make it a candidate for drug development.
- Cosmetics: Due to its biological activity, it may be incorporated into skin care products for its beneficial effects.
- Nutraceuticals: Potential use as a dietary supplement due to its health benefits associated with plant-derived compounds.
Interaction Studies of ruizgenin
Research on beta-Chlorogenin has focused on its interactions with biological macromolecules:
- Binding Studies: Investigations into how chlorogenin derivatives bind to viral proteins have revealed insights into their mechanisms of action against pathogens like H5N1.
- Cellular Interactions: Studies assessing the impact of chlorogenin on cell viability and function have provided data on its cytotoxicity and potential therapeutic effects.
Beta-Chlorogenin shares structural similarities with several other compounds. Here are some notable comparisons:
| Compound Name | Structural Features | Unique Aspects |
|---|---|---|
| Chlorogenin | Steroidal structure with hydroxyl groups | Precursor to beta-Chlorogenin; similar properties |
| Diosgenin | Similar steroidal backbone | Known for anti-inflammatory effects |
| Yamogenin | Contains additional functional groups | Unique in its application in traditional medicine |
| Sitosterol | Plant sterol with similar core structure | Primarily known for cholesterol-lowering effects |
Biological Activity of ruizgenin
Beta-Chlorogenin exhibits a range of biological activities, including:
- Antiviral Properties: Studies have shown that chlorogenin derivatives can inhibit the hemagglutinin protein of viruses such as H5N1, suggesting potential use in antiviral therapies.
- Cytotoxicity: Some derivatives have demonstrated cytotoxic effects against cancer cell lines, indicating potential applications in oncology.
- Hemolytic Activity: This compound has been noted for its hemolytic properties, which may be relevant in pharmacological contexts.